Fig. 5. Variation in Akt and ERK 1/2 phosphorylation (A and B) and in Cleaved Caspase 9 and Cytochrome C expression (C and D) in RPE cells, measured by Western blot and densitometric analysis. Densitometric analysis and an example of Western blot taken from 5 different experiments are shown in Fig.s A and B for p-Akt and p-ERK1/2, respectively, and in C and D for Cleaved Caspase 9 and Cytochrome C, respectively. Abbreviations are as in previous Fig.s. The data were normalized versus control value. Reported data are means ± SD of five independent experiments for each experimental protocol. Significance between groups: *P<0.05 vs C; #P<0.05 vs 200 μM H₂O₂.